Evaluation of the Potency of Anti-HIV and Anti-HCV Drugs to Inhibit P-Glycoprotein Mediated Efflux of Digoxin in Caco-2 Cell Line and Human Precision-Cut Intestinal Slices.

by Huličiak, Martin, Vokřál, Ivan, Holas, Ondřej, Martinec, Ondřej, Štaud, František, Červený, Lukáš
Published in Pharmaceuticals (14248247) (Feb2022)

Assessing the Anthelmintic Candidates BLK127 and HBK4 for Their Efficacy on Haemonchus contortus Adults and Eggs, and Their Hepatotoxicity and Biotransformation.

by Zajíčková, Markéta, Prchal, Lukáš, Vokřál, Ivan, Nguyen, Linh Thuy, Kurz, Thomas, Gasser, Robin, Bednářová, Klára, Mičundová, Magdalena, Lungerich, Beate, Michel, Oliver, Skálová, Lenka
Published in Pharmaceutics (Apr2022)

Environmental circulation of the anthelmintic drug albendazole affects expression and activity of resistance-related genes in the parasitic nematode Haemonchus contortus.

by Dimunová, Diana, Matoušková, Petra, Navrátilová, Martina, Nguyen, Linh Thuy, Ambrož, Martin, Vokřál, Ivan, Szotáková, Barbora, Skálová, Lenka
Published in Science of the Total Environment (May2022)

Metabolism of drugs and other xenobiotics in giant liver fluke ( Fascioloides magna ).

by Prchal, Lukáš, Vokřál, Ivan, Kašný, Martin, Rejšková, Lenka, Zajíčková, Markéta, Lamka, Jiří, Skálová, Lenka, Lecová, Lenka, Szotáková, Barbora
Published in Xenobiotica (Feb2016)

Ivermectin environmental impact: Excretion profile in sheep and phytotoxic effect in Sinapis alba.

by Vokřál, Ivan, Michaela, Šadibolová, Radka, Podlipná, Jiří, Lamka, Lukáš, Prchal, Dominika, Sobotová, Kateřina, Lokvencová, Barbora, Szotáková, Lenka, Skálová
Published in Ecotoxicology & Environmental Safety (Mar2019)

Proof of the environmental circulation of veterinary drug albendazole in real farm conditions.

by Navrátilová, Martina, Raisová Stuchlíková, Lucie, Matoušková, Petra, Ambrož, Martin, Lamka, Jiří, Vokřál, Ivan, Szotáková, Barbora, Skálová, Lenka
Published in Environmental Pollution (Oct2021)

Biotransformation of flubendazole and fenbendazole and their effects in the ribwort plantain (Plantago lanceolata).

by Stuchlíková, Lucie Raisová, Skálová, Lenka, Szotáková, Barbora, Syslová, Eliška, Vokřál, Ivan, Vaněk, Tomáš, Podlipná, Radka
Published in Ecotoxicology & Environmental Safety (Jan2018)

Human and rat precision-cut intestinal slices as ex vivo models to study bile acid uptake by the apical sodium-dependent bile acid transporter.

by Li, Ming, Vokral, Ivan, Evers, Bernard, de Graaf, Inge A.M., de Jager, Marina H., Groothuis, Geny M.M.
Published in European Journal of Pharmaceutical Sciences (Aug2018)

In vitro oxidative metabolism of xenobiotics in the lancet fluke ( Dicrocoelium dendriticum) and the effects of albendazole and albendazole sulphoxide ex vivo.

by Bártíková, Hana, Vokřál, Ivan, Skálová, Lenka, Lamka, Jiří, Szotáková, Barbora
Published in Xenobiotica (Sep2010)

The Role of Xenobiotic-Metabolizing Enzymes in Anthelmintic Deactivation and Resistance in Helminths.

by Matoušková, Petra, Vokřál, Ivan, Lamka, Jiří, Skálová, Lenka
Published in Trends in Parasitology (Jun2016)

Investigation of the metabolism of monepantel in ovine hepatocytes by UHPLC/MS/MS.

by Stuchlíková, Lucie, Jirásko, Robert, Vokřál, Ivan, Lamka, Jiří, Špulák, Marcel, Holčapek, Michal, Szotáková, Barbora, Bártíková, Hana, Pour, Milan, Skálová, Lenka
Published in Analytical & Bioanalytical Chemistry (Feb2013)

Xenobiotic-metabolizing enzymes in plants and their role in uptake and biotransformation of veterinary drugs in the environment.

by Bártíková, Hana, Skálová, Lenka, Stuchlíková, Lucie, Vokřál, Ivan, Vaněk, Tomáš, Podlipná, Radka
Published in Drug Metabolism Reviews (Aug2015)

Structural characterization of electrochemically and in vitro biologically generated oxidation products of atorvastatin using UHPLC/MS/MS.

by Jirásko, Robert, Mikysek, Tomáš, Chagovets, Vitaliy, Vokřál, Ivan, Holčapek, Michal
Published in Analytical & Bioanalytical Chemistry (Sep2013)

Reliable reference gene selection for quantitative real time PCR in Haemonchus contortus.

by Lecová, Lenka, Růžičková, Michaela, Laing, Roz, Vogel, Heiko, Szotáková, Barbora, Prchal, Lukáš, Lamka, Jiří, Vokřál, Ivan, Skálová, Lenka, Matoušková, Petra
Published in Molecular & Biochemical Parasitology (Jun2015)

Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo.

by Stuchlíková, Lucie, Matoušková, Petra, Bártíková, Hana, Vokřál, Ivan, Lamka, Jiří, Štolcová, Tereza, Pětníková, Hana, Szotáková, Barbora, Kubíček, Vladimír, Skálová, Lenka
Published in Chemico-Biological Interactions (Feb2015)

Biotransformation of benzimidazole anthelmintics in reed (Phragmites australis) as a potential tool for their detoxification in environment.

by Podlipná, Radka, Skálová, Lenka, Seidlová, Helena, Szotáková, Barbora, Kubíček, Vladimír, Stuchlíková, Lucie, Jirásko, Robert, Vaněk, Tomáš, Vokřál, Ivan
Published in Bioresource Technology (Sep2013)